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In pursuit of biological synergy, this paper will further discuss a second-year design studio project, Biological Booleans: home grown geometric solids, in a Fall term design studio. This project served as a bridge project that mediated students’ transition from first year to second year curriculum. The students were given a warm-up exercise that assisted in the transition from first year, introduced a prescriptive design process, and an overview of working with bio-composite materials, mycelium. It is imperative to educate the beginning design student on the notions of biomaterial applications to aid in their understanding of their potential to alter the building practices in the future.